MRPS6

GENE INFORMATION

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Gene name

MRPS6 (HGNC Symbol)

Synonyms

C21orf101, MRP-S6, RPMS6

Description

Mitochondrial ribosomal protein S6 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S6P family. Pseudogenes corresponding to this gene are found on chromosomes 1p and 12q. [provided by RefSeq, Jul 2008]

Chromosome

21

Cytoband

q22.11

Chromosome location (bp)

34073224 - 34143034

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000243927 (version 78.38)

Entrez gene

64968

UniProt

P82932 (UniProt - Evidence at protein level)

neXtProt

NX_P82932

Antibodypedia

MRPS6 antibodies
 

PROTEIN VIEW

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MRPS6-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPS6-001 ENSP00000382250
ENST00000399312
P82932
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