DDOST

GENE INFORMATION

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Gene name

DDOST (HGNC Symbol)

Synonyms

KIAA0115, OST, OST48, WBP1

Description

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) (HGNC Symbol)

Entrez gene summary

This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p36.12

Chromosome location (bp)

20651767 - 20661544

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000244038 (version 78.38)

Entrez gene

1650

UniProt

P39656 (UniProt - Evidence at protein level)

neXtProt

NX_P39656

Antibodypedia

DDOST antibodies
 

PROTEIN VIEW

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DDOST-001
 
DDOST-005
 
DDOST-006
 
DDOST-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DDOST-001 ENSP00000364188
ENST00000375048
P39656
Show all »
Show » Show » 456 50.8 Yes 1
DDOST-005 ENSP00000475634
ENST00000464364
U3KQ84
Show all »
Show » Show » 155 17.2 Yes 0
DDOST-006 ENSP00000473655
ENST00000602624
P39656
Show all »
Show » Show » 439 48.8 Yes 1
DDOST-201 ENSP00000399457
ENST00000415136
P39656
Show all »
Show » Show » 456 50.8 Yes 1