ITGB3

GENE INFORMATION

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Gene name

ITGB3 (HGNC Symbol)

Synonyms

CD61, GP3A, GPIIIa

Description

Integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (HGNC Symbol)

Entrez gene summary

The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q21.32

Chromosome location (bp)

47253846 - 47311816

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000259207 (version 78.38)

Entrez gene

3690

UniProt

P05106 (UniProt - Evidence at protein level)

neXtProt

NX_P05106

Antibodypedia

ITGB3 antibodies
 

PROTEIN VIEW

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ITGB3-001
 
ITGB3-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ITGB3-001 ENSP00000452786
ENST00000559488
P05106
Show all »
Show » Show » 788 87.1 Yes 1
ITGB3-004 ENSP00000461626
ENST00000571680
I3L4X8
Show all »
Show » Show » 443 48.7 Yes 0