CCR6

GENE INFORMATION

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Gene name

CCR6 (HGNC Symbol)

Synonyms

BN-1, CD196, CKR-L3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, STRL22

Description

Chemokine (C-C motif) receptor 6 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

q27

Chromosome location (bp)

166999405 - 167139141

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000272980 (version 78.38)

Entrez gene

1235

UniProt

neXtProt

Antibodypedia

CCR6 antibodies
 

PROTEIN VIEW

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CCR6-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCR6-201 ENSP00000383715
ENST00000400926
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