MRPL23

GENE INFORMATION

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Gene name

MRPL23 (HGNC Symbol)

Synonyms

L23MRP, RPL23L

Description

Mitochondrial ribosomal protein L23 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. The gene is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11. [provided by RefSeq, Jul 2008]

Chromosome

Unmapped

Cytoband

Chromosome location (bp)

2585 - 11802

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000276345 (version 78.38)

Entrez gene

6150

UniProt

neXtProt

Antibodypedia

MRPL23 antibodies
 

PROTEIN VIEW

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MRPL23-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL23-201 ENSP00000478035
ENST00000612848
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