HIST1H2AE

GENE INFORMATION

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Gene name

HIST1H2AE (HGNC Symbol)

Synonyms

H2A.1, H2A/a, H2AFA

Description

Histone cluster 1, H2ae (HGNC Symbol)

Entrez gene summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

p22.2

Chromosome location (bp)

26216975 - 26217367

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000277075 (version 78.38)

Entrez gene

3012

UniProt

P04908 (UniProt - Evidence at protein level)

neXtProt

NX_P04908

Antibodypedia

HIST1H2AE antibodies
 

PROTEIN VIEW

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HIST1H2AE-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HIST1H2AE-001 ENSP00000303373
ENST00000303910
P04908
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