GPIHBP1

GENE INFORMATION

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Gene name

GPIHBP1 (HGNC Symbol)

Synonyms

GPI-HBP1, LOC338328

Description

Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a capillary endothelial cell protein that facilitates the lipolytic processing of triglyceride-rich lipoproteins. The encoded protein is a glycosylphosphatidylinositol-anchored protein that is a member of the lymphocyte antigen 6 (Ly6) family. This protein plays a major role in transporting lipoprotein lipase (LPL) from the subendothelial spaces to the capillary lumen. Mutations in this gene are the cause of hyperlipoproteinemia, type 1D. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Chromosome

8

Cytoband

q24.3

Chromosome location (bp)

143213193 - 143217170

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000277494 (version 78.38)

Entrez gene

338328

UniProt

Q8IV16 (UniProt - Evidence at protein level)

neXtProt

NX_Q8IV16

Antibodypedia

GPIHBP1 antibodies
 

PROTEIN VIEW

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GPIHBP1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GPIHBP1-001 ENSP00000480053
ENST00000622500
Q8IV16
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